Dysbiosis; (microbial imbalances) can play a role in systemic immune inflammatory response. Causes of this dysbiosis are; diet and nutritional status, stress, decreased immune status, decrease gut motility, maldigestion, internal infection, xenobiotics, increased intestinal PH, diabetes, scleroderma, gastrointestinal tract surgery, and nutritional and microbial deficiencies.
Microflora promotes a healthy GI tract barrier, develops and supports GALT (Gut Associated Lymphoid Tissue), digests large carbohydrates, affects transit times through the intestines, prevents pathogen functions, metabolic fermentation, vitamin synthesis, energy production, and epithelial cell differentiation.
Probiotics produce cytochrome P450 like enzymes which help with detoxification. Produce some B vitamins and vitamin K. Aids digestion, enhances absorption, combats diarrhoea, interacts with immune system to improve resistance, exerts antimutagenic and anti tumour actions, and exhibit imminomodulation effects.
Imbalances can have a profound effect on oestrogen levels, carcinogen and immune related diseases. Support can involve the use of; probiotics, prebiotics and nutrients supporting the intestinal mucosa. All of which help to restore optimal permeability of the intestine.The bacteria used in supplementation are; Bifidobacterium, lactobacillus, and streptococci. Prebiotic support it Is also crucial; oats , flaxseed, onions and garlic, bananas, lentils, and artichoke. Nutritional support for intestinal mucosal cells include, glutamine, which is the principal metabolic fuel used by cells of the small intestine, Butyric acid which is the fuel used by the large intestine, and EPA and GLA. Omegas 3 and 6 which support regulation of the inflammatory response.
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