- Inflammatory Disordes
Either due to contact with offending agent; contact dermatitis, or a type IV hypersensitivity reaction; atopic dermatitis. Symptoms; acutely, red, oozing, pruritic, and crusted lesions. Chronically may develop into raised. poorly defined, scaling plaques. Treatment corticosteroids, removal of aggravating agent, antihistamines.
Aetiology unknown, possibly due to autoimmunity and genetic predisposition. Symptoms; coral-coloured plaque covered with silver scales, usually located on scalp, elbows and knees. Removal of scale results in bleeding. Nail discolouration with separation of nail plate from nail bed. Associated with psoriatic arthritis. Treatment; corticosteroids, UVB light exposure.
Pemphigus Vulgaris and Bullous PemphigoidAutoimmune conditions characterised by involvement of IgG antibodies. Pemphigus Vulgaris causes painful blisters to develop on the skin, as well as the inside of the mouth. Can easily burst leaving areas of raw unhealed skin. Treatment, corticosteroids. Bullous Pemphigoid, blistering eruptions on the surface of the skin and occasionally within mucous membrane linings of the mouth, nose and eye. Symptoms will include itching and burning sensations and possibly nosebleeds. Treatment, systemic corticosteroids and immunosuppressants.